Probiotic Therapy May Prevent Obesity
The health of our internal flora, or gut bacteria, has been an area of intense study and research over the past decade as scientist search for ways to combat the growing obesity epidemic. Previous studies have linked inadequate gut bacteria to chronic diseases such as inflammatory bowel disease, diabetes, and cardiovascular disease. However, a new study published in the Journal of Clinical Investigation has found that probiotic therapy has the ability to prevent diabetes and weight gain in a mouse model study conducted by researchers at Vanderbilt University. For the study researchers added a lipid compound identified as NAPE, which is produced in the small intestine by the bacteria E.Coli Nissle, to the water of overweight mice who were being fed a high fat diet for eight weeks. During the eight week trial researchers observed that the mice lost weight, had much lower body fat, and continued to show improvements in body composition for up to 12 weeks post therapy although no active bacteria is present in the gut after six weeks. The researchers are now developing methods and procedures to see if their work will translate in human trials.
http://www.sciencedaily.com/releases/2014/07/140722142521.htm
Study Links Carbs And Colon Cancer
Some anthropologists believe that the development of chronic disease didn’t begin to occur until after the agricultural revolution when humans were able to farm and harvest significant amounts of grain for the first time. Current studies of hunter gatherer cultures show that they are relatively disease free, and the sicknesses associated with modern society don’t development until the introduction of farmed and processed carbohydrates such as flour, rice, and sugar become a part of their diet. A new study conducted by researchers at the University of Toronto has found that consuming carbohydrates is responsible for the growth of specific types of bacteria in the colon that cause polyps – which can then develop into cancer. According to researchers the bacteria clostridia converts glucose into a metabolite known as butyrate. When butyrate is overproduced it causes a rapid increase in the development of potentially cancer causing polyps. Researchers believe that it may be our increased consumption of carbohydrates that is causing a dramatic rise in the incidences of colon cancer, which is responsible for killing nearly 50,000 people in the United States every year. They suggest that by reducing carbohydrate intake and limiting the ingestion of refined sugars individuals can significantly reduce their risk for the development of colorectal cancer.
http://www.psmag.com/navigation/health-and-behavior/links-carbs-gut-microbes-colon-cancer-86437/
Ketogenic Diets Improve Athletic Performance
In the bodybuilding world ketogenic diets have gained popularity for their ability to help athletes quickly shed body fat while avoiding the brain fog typically associated with endless weeks of low carb dieting. Although some debate their efficacy, and certain mainstream “health experts” claim that they’re dangerous, the effectiveness of ketogenic diets has been proven empirically and scientifically for decades. According to a new study published in Sport and Performance Nutrition ketogenic diets have the ability to improve athletic performance and body composition in off-road cyclists. For the study researchers took two groups of well-trained cyclists and placed them on either a ketogenic, or traditional mixed diet, and had them perform a continuous exercise protocol on a cycloergometer. According to the data they collected from their experiment the participants on the ketogenic diet showed favorable improvements on blood lipid profiles, and increase in VO2 max, increased fat oxidation, and lower heart rates during certain stages of the exercise protocol and while at rest. Although the results of the study do not prove conclusively that ketogenic diets positively impact all forms of athletic training, they do show that ketogenic diets in conjunction with exercise could provide a number of desirable health and performance benefits.
http://www.mdpi.com/2072-6643/6/7/2493#tabs-5
Sleeping In Cooler Temperatures Activates Fat Burning Fat
Humans have two different types of adipose (fat) tissue in the body. White adipose tissue is the metabolically inactive storage depot for excess energy responsible for us for making life difficult during contest prep. However brown adipose tissue, also known as the fat burning fat, is a metabolically active tissue that has thermo genic properties and has been shown to become activated during periods of exposure to cold. A recent study published by the American Diabetes Associations shows that sleeping in cold temperatures has the ability to activate our stores of fat burning fat and influence the productions of the fat storing hormones leptin and adiponectin. For the study researchers had subjects sleep in a temperature controlled environment for four consecutive months to see how temperature would influence brown fat activation at rest. Researchers found that not only did sleeping in cooler temperatures have a greater impact on brown fat activation, but it also appeared to enhance insulin sensitivity after meals and increase diet induced thermogenesis. Now the race is on to see who will be sleeping in cold temperatures, or regular cryo-therapy - which has recently become very popular with athletes – to bring an anatomy chart-like level of conditioning to the stage.
http://www.ncbi.nlm.nih.gov/pubmed/24954193
Single Injection Cures Diabetes In Mice
Type-2 diabetes develops over time when chronically high blood sugars desensitize muscle and liver cells to the hormone insulin which is responsible for transporting glucose through the blood and into cells. When insulin resistance occurs due to chronically high blood sugars substances known as advanced glycation end products form and bind to proteins in the blood and cause a tremendous amount damage to cells and tissues as they accumulate. Recently a new study conducted by Salk University has discovered that a protein known as FGF1 has demonstrated the ability to cure insulin resistance and reverse type-2 diabetes in mice. Researcher’s injected overweight diabetic mice just once with the protein and found that it began to resensitize insulin resistant cells and lower blood sugar almost immediately. Researchers found that even when administered at high doses the drug did not cause sudden drops in blood sugar resulting in hypoglycemia, and that with regular injections symptoms of non-alcoholic fatty liver appeared to reverse as well. The new findings have made researchers optimistic that they may have discovered as safe and effective long term treatment option that could revolutionize the way diabetes therapies are handled in the future.
http://www.sciencedaily.com/releases/2014/07/140716131541.htm
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